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AI Technology Identifies Hidden Chronic Stress Biomarker in CT Scans

Update How CT Scans Are Now Uncovering Chronic StressIn an exciting leap for medical imaging, researchers from Johns Hopkins University have harnessed the power of artificial intelligence to unveil a new biomarker of chronic stress visible in standard chest CT scans. This breakthrough could transform how we understand and measure the long-term impacts of stress on health, particularly concerning conditions like heart disease and obesity.The deep learning model they developed calculates what's known as the Adrenal Volume Index (AVI)—an innovative metric derived from the size of adrenal glands observed in CT images. Studies show strong correlations between increased adrenal volumes and higher levels of cortisol, perceived stress, and allostatic load—a composite measure of everything the body endures from chronic stress. It’s a game changer, as chronic stress has previously been challenging to quantify using medical imaging.Understanding the Health Risks of Chronic StressChronic stress isn't just a buzzword; it's a significant health concern linked to various ailments, including heart disease, depression, and metabolic syndromes. According to the American Psychological Association, the toll it takes on mental and physical health is profound, leading to symptoms such as anxiety, sleep disturbances, and increased blood pressure.The research team analyzed data from 2,842 participants in a major study reflecting a diverse demographic. What makes this research stand out is its unique combination of imaging data, salivary cortisol levels, and psychosocial assessments, allowing for a comprehensive look at stress’s multifaceted impact on health.Revolutionizing Stress Assessment in HealthcareFor the first time, healthcare providers will have a tangible way to observe chronic stress's physical manifestations within the body. Traditionally, assessments have relied on subjective questionnaires or singular cortisol tests, which don’t account for stress over time. The ability to visualize stress through the Adrenal Volume Index is a monumental step in preventive care.Dr. Elena Ghotbi, the study’s lead author, emphasizes that this model opens opportunities for far-reaching implications in large-scale health evaluations. “Our approach leverages widely available imaging data,” she explains, “opening the door to comprehensive evaluations of the biological impacts of chronic stress using existing chest CT scans.” Future Directions and Health ImplicationsThe implications of this research are vast. With routine imaging data that already exists in hospitals across the country, clinicians can better stratify cardiovascular risks directly associated with stress. This could lead to earlier interventions and a focus on preventive strategies to reduce the burden of chronic stress on overall health and wellbeing.Dr. Shadpour Demehri, a senior author of the study, indicates that this research marks a significant leap forward in operationalizing how we can measure and understand the cumulative impact of stress. This newfound ability will empower individuals and healthcare professionals alike to recognize stress as a key factor in healthcare and lifestyle adjustments.