Hidden Heart Risks: The Dark Side of Long-Term Melatonin Use

Melatonin Use and Heart Health: What You Need to Know

Melatonin has long been viewed as a harmless natural remedy for sleep issues. However, recent research from the American Heart Association reveals troubling connections between long-term use of melatonin and heart health risks. While melatonin helps many people fall asleep, chronic users—those taking it for more than a year—may face a staggering 90% higher risk of developing heart failure compared to non-users.

This revelation raises critical concerns about the assumed safety of melatonin, especially since its popularity has skyrocketed in recent years. In a study involving more than 130,000 adults suffering from insomnia, researchers discovered that those using melatonin regularly were almost twice as likely to die from any cause. As this evidence mounts, sleep experts urge caution and further investigation into the long-term cardiovascular implications of this supplement.

The Surprising Risks of 'Natural' Sleep Aids

Most people perceive melatonin as a safe go-to option for sleep difficulties due to its status as a natural hormone. However, the study presented at the AHA's Scientific Sessions 2025 casts doubt on this common belief. While melatonin supplements can be effective for short-term use, prolonged reliance may inadvertently complicate one's health—especially cardiovascular health.

Dr. Ekenedilichukwu Nnadi, the study's lead author, suggests that this new information may change how healthcare providers recommend sleep aids. The inconsistency in supplement quality and dosages, as melatonin is often unregulated, adds to the complexity of its use and highlights the importance of professional guidance.

Red Flags: Understanding Insomnia and Melatonin Use

Chronic insomnia affects up to 10% of American adults, who often look to melatonin as a solution for their sleep issues. But what many don’t realize is that persistent sleep disturbances can be indicators of deeper health problems. The fact that the study hints at a potential correlation between long-term melatonin use and increased cardiovascular risk is a wake-up call.

Experts like Dr. Rigved Tadwalkar emphasize the importance of addressing the root causes of sleep difficulties rather than masking them with supplements like melatonin. Individuals could benefit by consulting sleep specialists to better understand their sleep patterns.

Strategies for Healthy Sleep Without Melatonin

Fortunately, there are numerous ways to enhance sleep quality without relying on supplements. Experts recommend establishing a bedtime routine, reducing caffeine and alcohol intake before bed, and creating a calming sleep environment. Cognitive Behavioral Therapy (CBT) has also shown promising results in addressing the behaviors and thought patterns that contribute to insomnia.

Incorporating these practices can lead to improved overall health and a decrease in the risks associated with chronic insomnia, such as high blood pressure and heart disease. Prioritizing sleep hygiene is crucial for maintaining heart health and overall well-being.

A Cautious Path Forward

As studies like this dominate the conversation, the takeaway is clear: while melatonin may seem like an innocuous option for better sleep, users should engage in a conversation with their healthcare provider to discuss safe practices and alternatives. Ensuring proper sleep hygiene and addressing underlying sleep issues could lead to a healthier life without the risks posed by long-term melatonin use.